Name: 12,14-Dichlorodehydroabietic acid
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214323973
Cas No:65281-77-8
常用名:12,14-Dichlorodehydroabietic acid
常用名:12,14-Dichlorodehydroabietic acid
别名:二氯脱氢松香酸
IUPAC:(1R,4aS,10aR)-6,8-dichloro-1,4a-dimethyl-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid
IUPAC:(1R,4aS,10aR)-6,8-dichloro-1,4a-dimethyl-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid
InChI key:RKQWIQSTFSBVMQ-CDHQVMDDSA-N

分子式:C20H26Cl2O2
分子量:369.33
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[H][C@@]12CCc3c(Cl)c(C(C)C)c(Cl)cc3[C@@]1(C)CCC[C@@]2(C)C(O)=O
SMILES:[H][C@@]12CCc3c(Cl)c(C(C)C)c(Cl)cc3[C@@]1(C)CCC[C@@]2(C)C(O)=O

12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity. It effectively inhibits GABA-dependent chloride influx in the mammalian brain, functioning as a non-competitive antagonist of GABA A receptors. Moreover, 12,14-Dichlorodehydroabietic acid induces an elevation in cytosolic free calcium levels and promotes the release of neurotransmitters.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~