Name: Benzyl-PEG9-THP
Rating: 5 (10 reviews)

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结构编辑

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HIT ID:HIT214323997
Cas No:669556-53-0
常用名:Benzyl-PEG9-THP
别名:Benzyl-PEG9-THP
IUPAC:2-[(1-phenyl-2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl)oxy]oxane
IUPAC:2-[(1-phenyl-2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl)oxy]oxane
InChI key:UPOGSHHHOLZUFV-UHFFFAOYSA-N

分子式:C30H52O11
分子量:588.735
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:C(COCCOCCOCCOCCOC1CCCCO1)OCCOCCOCCOCCOCc1ccccc1
SMILES:C(COCCOCCOCCOCCOC1CCCCO1)OCCOCCOCCOCCOCc1ccccc1

Benzyl-PEG9-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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