Name: Glucocorticoids receptor agonist 1
Rating: 5 (10 reviews)

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HIT ID:HIT214324009
Cas No:694526-54-0
常用名:Glucocorticoids receptor agonist 1
常用名:Glucocorticoids receptor agonist 1
IUPAC:(1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl]ethan-1-ol
IUPAC:(1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH,5H,6H,7H,8H-cyclohexa[f]indazol-5-yl]ethan-1-ol
InChI key:GZUNIDQZQNDLTI-VIZZQPHQSA-N

分子式:C20H23FN2O
分子量:326.415
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@H](C)O |t:5|
SMILES:[H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@H](C)O |t:5|

Glucocorticoids receptor agonist 1 (GRA-1) is a highly effective arylpyrazole-based compound that acts as an agonist for the glucocorticoid receptor. GRA-1 exhibits strong anti-inflammatory properties while maintaining insulin secretion function.

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