Name: ACG548B
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214324076
Cas No:795316-16-4
常用名:ACG548B
IUPAC:4-[(4-chlorophenyl)(methyl)amino]-1-{[3'-({4-[(4-chlorophenyl)(methyl)amino]pyridin-1-ium-1-yl}methyl)-[1,1'-biphenyl]-3-yl]methyl}pyridin-1-ium dibromide
IUPAC:4-[(4-chlorophenyl)(methyl)amino]-1-{[3'-({4-[(4-chlorophenyl)(methyl)amino]pyridin-1-ium-1-yl}methyl)-[1,1'-biphenyl]-3-yl]methyl}pyridin-1-ium dibromide
InChI key:ZFCCRPWNWOHZEN-UHFFFAOYSA-L

分子式:C38H34Br2Cl2N4
分子量:777.43
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[Br-].[Br-].CN(c1ccc(Cl)cc1)c1cc[n+](Cc2cccc(c2)-c2cccc(C[n+]3ccc(cc3)N(C)c3ccc(Cl)cc3)c2)cc1
SMILES:[Br-].[Br-].CN(c1ccc(Cl)cc1)c1cc[n+](Cc2cccc(c2)-c2cccc(C[n+]3ccc(cc3)N(C)c3ccc(Cl)cc3)c2)cc1

ACG548B (compound 24) is a highly effective inhibitor of acetyl- and butyrylcholinesterase (AChE and BChE) with IC50 values of 1.78 and 0.496 μM, respectively. It exhibits a greater affinity for AChE and demonstrates selectivity over BChE and ChoK (choline kinase).

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~