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  3. HIT214324116
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HIT214324116
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HIT214324116
  • HIT ID:HIT214324116
  • Cas No:859518-94-8
  • 常用名:T0467
  • 别名:T0467
  • IUPAC:N-[2-(3,5-difluorophenyl)ethyl]-4-(2-fluoro-5-{[(2S)-2-methylpiperazin-1-yl]methyl}phenyl)pyrimidin-2-amine
    IUPAC:N-[2-(3,5-difluorophenyl)ethyl]-4-(2-fluoro-5-{[(2S)-2-methylpiperazin-1-yl]methyl}phenyl)pyrimidin-2-amine
  • InChI key:GNYKYGZGDGZPOK-INIZCTEOSA-N
  • 分子式:C24H26F3N5
  • 分子量:441.502
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:C[C@H]1CNCCN1Cc1ccc(F)c(c1)-c1ccnc(NCCc2cc(F)cc(F)c2)n1
    SMILES:C[C@H]1CNCCN1Cc1ccc(F)c(c1)-c1ccnc(NCCc2cc(F)cc(F)c2)n1
  • T0467 is a chemical compound that activates the translocation of parkin to the mitochondria in a PINK1-dependent manner in vitro. However, T0467 does not induce the accumulation of PINK1 in the mitochondria of dopaminergic neurons. As a result, T0467 shows promise as a potential compound for activating the PINK1-Parkin signaling pathway and can be utilized in research related to Parkinson's disease and related disorders.
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  • 供应商
    TargetMolSC
    规格
    货期
    5日内发货
    纯度
    -
    ¥ 1,820.00
    1

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