Name: LP-184
Rating: 5 (10 reviews)

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sdf 文件

结构编辑

类似物检索

HIT ID:HIT214324179
Cas No:924835-67-6
常用名:LP-184
IUPAC:1-hydroxy-1-{[(6'R)-6'-hydroxy-2',4',6'-trimethyl-7'-oxo-6',7'-dihydrospiro[cyclopropane-1,5'-inden]-3'-yl]methyl}urea
IUPAC:1-hydroxy-1-{[(6'R)-6'-hydroxy-2',4',6'-trimethyl-7'-oxo-6',7'-dihydrospiro[cyclopropane-1,5'-inden]-3'-yl]methyl}urea
InChI key:VWMPVAZEBAKLFR-HNNXBMFYSA-N

分子式:C16H20N2O4
分子量:304.346
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC1=C(CN(O)C(N)=O)C2=C(C)C3(CC3)[C@@](C)(O)C(=O)C2=C1 |c:1,9,22|
SMILES:CC1=C(CN(O)C(N)=O)C2=C(C)C3(CC3)[C@@](C)(O)C(=O)C2=C1 |c:1,9,22|

LP-184 (Compound 6), referred to as an acylfulvene analog, demonstrates the ability to inhibit tumor growth with noteworthy anti-cancer efficacy observed across multiple cell lines, including ovarian, colon, prostate, and pancreatic.

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