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  3. HIT214432730
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HIT214432730
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HIT214432730
  • HIT ID:HIT214432730
  • Cas No:2756458-77-0
  • 常用名:MAT2A-IN-7
  • IUPAC:1-(2-chlorophenyl)-3-methoxy-4-(methylamino)-7-(trifluoromethyl)-1,2-dihydro-1,8-naphthyridin-2-one
    IUPAC:1-(2-chlorophenyl)-3-methoxy-4-(methylamino)-7-(trifluoromethyl)-1,2-dihydro-1,8-naphthyridin-2-one
  • InChI key:SXJCTUGSTQFFCW-UHFFFAOYSA-N
  • 分子式:C17H13ClF3N3O2
  • 分子量:383.76
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CNc1c(OC)c(=O)n(-c2ccccc2Cl)c2nc(ccc12)C(F)(F)F
    SMILES:CNc1c(OC)c(=O)n(-c2ccccc2Cl)c2nc(ccc12)C(F)(F)F
  • MAT2A-IN-7, a potent inhibitor of the enzyme MAT2A, demonstrates efficacy in targeting the abnormally elevated expression of MAT2A observed in gastric, colon, liver, and pancreatic cancers. Furthermore, MAT2A-IN-7 effectively reduces the proliferative activity specifically in MTAP-deficient cancer cells, thus highlighting its potential for cancer research applications [1].
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  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 14,900.00
    1

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