Name: HBV-IN-25
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214432744
Cas No:2161364-69-6
常用名:HBV-IN-25
IUPAC:(3R)-1-(5-chloro-9-oxo-9H-xanthen-3-yl)pyrrolidine-3-carboxylic acid
IUPAC:(3R)-1-(5-chloro-9-oxo-9H-xanthen-3-yl)pyrrolidine-3-carboxylic acid
InChI key:DHVRTFMBTRRBRG-SNVBAGLBSA-N

分子式:C18H14ClNO4
分子量:343.76
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:OC(=O)[C@@H]1CCN(C1)c1ccc2c(c1)oc1c(Cl)cccc1c2=O
SMILES:OC(=O)[C@@H]1CCN(C1)c1ccc2c(c1)oc1c(Cl)cccc1c2=O

HBV-IN-25 is a novel chemical compound that acts as a potent HBV cccDNA reducer when administered orally. It exhibits significant anti-HBeAg potency and anti-HBV activity, with IC50 values of 0.58 μM and 1.15 μM, respectively. Moreover, HBV-IN-25 demonstrates favorable aqueous solubility (LYSA＞452 μg/mL) and no cellular toxicity, making it a promising candidate for further investigation and development [1].

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~