HP1328 | CAS 2245074-20-6 | AnyMole

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HIT214432752

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HIT214432752

HIT ID:HIT214432752
Cas No:2245074-20-6
常用名:HP1328
IUPAC:2-(2-methoxy-4-{[(1-phenyl-1H-1,3-benzodiazol-5-yl)amino]methyl}phenoxy)ethan-1-ol
IUPAC:2-(2-methoxy-4-{[(1-phenyl-1H-1,3-benzodiazol-5-yl)amino]methyl}phenoxy)ethan-1-ol
InChI key:FNNZOQPZURDRII-UHFFFAOYSA-N

分子式:C23H23N3O3
分子量:389.455
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:COc1cc(CNc2ccc3n(cnc3c2)-c2ccccc2)ccc1OCCO
SMILES:COc1cc(CNc2ccc3n(cnc3c2)-c2ccccc2)ccc1OCCO

HP1328 is a highly effective inhibitor of FLT3 receptor tyrosine kinase with a specific focus on FLT3/ITD mutation. It belongs to the benzoimidazole scaffold-based compound family. Significantly reducing the leukemia burden, HP1328 effectively extends the survival of mice afflicted with FLT3/ITD leukemia [1].

市场产品/服务共显示2个结果

供应商
TargetMolSC
规格
货期
6-8周
纯度
-
¥ 10,600.00
1
供应商
EnamineSC
规格
货期
4-6周
纯度
-
¥ 1,373.00
1

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