Name: EIF2α activator 2
Rating: 5 (10 reviews)

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HIT ID:HIT214432787
Cas No:1501618-04-7
常用名:EIF2α activator 2
别名:EIF2α 激活剂 2
IUPAC:3-[(1r,4r)-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]-1-[3-(trifluoromethyl)phenyl]urea
IUPAC:3-[(1r,4r)-4-[4-(trifluoromethyl)phenoxy]cyclohexyl]-1-[3-(trifluoromethyl)phenyl]urea
InChI key:MFRDVPYKJUYMDN-RZDIXWSQSA-N

分子式:C21H20F6N2O2
分子量:446.393
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:FC(F)(F)c1ccc(O[C@H]2CC[C@@H](CC2)NC(=O)Nc2cccc(c2)C(F)(F)F)cc1
SMILES:FC(F)(F)c1ccc(O[C@H]2CC[C@@H](CC2)NC(=O)Nc2cccc(c2)C(F)(F)F)cc1

EIF2α activator 2 (Compound 1) is an activator of eIF2α phosphorylation, exhibiting anti-proliferative activity at the μM level in SRB, K562, and PBMC cells, suitable for cancer research.

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