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  3. HIT214433037
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HIT214433037
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HIT214433037
  • HIT ID:HIT214433037
  • Cas No:2480284-01-1
  • 常用名:hCAI/II-IN-4
  • IUPAC:cyclopropylmethyl 2-(4-sulfamoylbenzamido)-1,3-thiazole-4-carboxylate
    IUPAC:cyclopropylmethyl 2-(4-sulfamoylbenzamido)-1,3-thiazole-4-carboxylate
  • InChI key:GNWGBZOLHBOSHB-UHFFFAOYSA-N
  • 分子式:C15H15N3O5S2
  • 分子量:381.42
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:NS(=O)(=O)c1ccc(cc1)C(=O)Nc1nc(cs1)C(=O)OCC1CC1
    SMILES:NS(=O)(=O)c1ccc(cc1)C(=O)Nc1nc(cs1)C(=O)OCC1CC1
  • hCAI/II-IN-4 (compound 6d) is a powerful inhibitor of both hCA I and hCA II enzymes, with Ki values of 16.95 nM and 15.22 nM, respectively. It demonstrates inhibitory activity against hCA IX with a Ki value of 27.04 nM. Additionally, hCAI/II-IN-4 exhibits anti-hypoxia properties while maintaining low toxicity. This compound is suitable for investigating acute mountain sickness (AMS) in research studies [1].
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

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