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  3. HIT214433210
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HIT214433210
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HIT214433210
  • HIT ID:HIT214433210
  • Cas No:2711810-41-0
  • 常用名:DNA-PK-IN-6
  • IUPAC:7,20-dimethyl-2,4,7,9,17,22,24-heptaazapentacyclo[13.5.2.2^{3,6}.0^{5,9}.0^{18,22}]tetracosa-1(21),2,5,15,17,19,23-heptaen-8-one
    IUPAC:7,20-dimethyl-2,4,7,9,17,22,24-heptaazapentacyclo[13.5.2.2^{3,6}.0^{5,9}.0^{18,22}]tetracosa-1(21),2,5,15,17,19,23-heptaen-8-one
  • InChI key:DXOSNFFQQVJOOZ-UHFFFAOYSA-N
  • 分子式:C19H21N7O
  • 分子量:363.425
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:Cc1cc2ncc3CCCCCn4c5NC(N=Cc5n(C)c4=O)=Nc1cn23
    SMILES:Cc1cc2ncc3CCCCCn4c5NC(N=Cc5n(C)c4=O)=Nc1cn23
  • DNA-PK-IN-6, a robust DNA-PK inhibitor, effectively hampers the activity of DNA-PKcs, thereby significantly impairing the DNA repair mechanism in tumors and instigating apoptosis in cells. Additionally, DNA-PK-IN-6 amplifies the responsiveness of tumor tissues to radiotherapy, overcomes the challenge of drug resistance, and augments its inhibitory impact on a diverse range of solid and hematological tumors[1].
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    10-14周
    纯度
    -
    ¥ 14,900.00
    1

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