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- HIT ID:HIT214433395
- Cas No:675848-25-6
- 常用名:VO-OHPic
- InChI key:DUQTXODYOYERFR-UHFFFAOYSA-N
- 分子式:C12H10N2O8V
- 分子量:361.16
- 氢键供体数 (HBD):
- 氢键受体数 (HBA):
- LogP:
- VO-OHPic is a reversible, noncompetitive, and selective inhibitor of PTEN with an IC50 of 46 nM. It effectively attenuates apoptosis, adverse cardiac remodeling, and the presence of pro-inflammatory M1 macrophages in models of doxorubicin-induced cardiomyopathy. Additionally, VO-OHPic inhibits autophagy [1] [2] [3].
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- 供应商TargetMol规格货期35日内发货纯度-¥ 4,970.001
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