Name: XTT (sodium salt hydrate)
Rating: 5 (10 reviews)

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HIT ID:HIT214433601
Cas No:413585-64-5
常用名:XTT (sodium salt hydrate)
IUPAC:sodium 2,3-bis(2-methoxy-4-nitro-5-sulfonatophenyl)-5-(phenylcarbamoyl)-3H-1,2lambda5,3,4-tetrazol-2-ylium hydrate
IUPAC:sodium 2,3-bis(2-methoxy-4-nitro-5-sulfonatophenyl)-5-(phenylcarbamoyl)-3H-1,2lambda5,3,4-tetrazol-2-ylium hydrate
InChI key:OMYYRPUFIRZPOS-UHFFFAOYSA-M

分子式:C22H18N7NaO14S2
分子量:691.53
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:O.[Na+].COc1cc(c(cc1-n1nc(n[n+]1-c1cc(c(cc1OC)[N+]([O-])=O)S([O-])(=O)=O)C(=O)Nc1ccccc1)S([O-])(=O)=O)[N+]([O-])=O
SMILES:O.[Na+].COc1cc(c(cc1-n1nc(n[n+]1-c1cc(c(cc1OC)[N+]([O-])=O)S([O-])(=O)=O)C(=O)Nc1ccccc1)S([O-])(=O)=O)[N+]([O-])=O

XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator.1,2It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.3

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