Name: PPARγ agonist 3
Rating: 5 (10 reviews)

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HIT ID:HIT214434276
Cas No:2011801-48-0
常用名:PPARγ agonist 3
IUPAC:4'-[(2-propyl-1H-1,3-benzodiazol-1-yl)methyl]-[1,1'-biphenyl]-2-carboxamide
IUPAC:4'-[(2-propyl-1H-1,3-benzodiazol-1-yl)methyl]-[1,1'-biphenyl]-2-carboxamide
InChI key:VTPVHUKEMCBVSN-UHFFFAOYSA-N

分子式:C24H23N3O
分子量:369.468
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(N)=O
SMILES:CCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(N)=O

PPARγ agonist 3, also known as Compound 18a, is a potent and selective agonist of PPARγ. This compound does not exhibit cytotoxicity towards both non-resistant and resistant cells. Notably, PPARγ agonist 3 demonstrates antitumor efficacy exclusively when co-administered with Imatinib [1].

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