Name: Trk-IN-20
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214434334
Cas No:2460924-63-2
常用名:Trk-IN-20
IUPAC:N-[(1R)-1-(3,5-difluorophenyl)ethyl]-3-[(1E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-5-amine
IUPAC:N-[(1R)-1-(3,5-difluorophenyl)ethyl]-3-[(1E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-5-amine
InChI key:ZHOXAGNPCZTRBN-HZRUHFOJSA-N

分子式:C22H18F2N4
分子量:376.411
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:C[C@@H](Nc1ccc2[nH]nc(\C=C\c3ccccn3)c2c1)c1cc(F)cc(F)c1
SMILES:C[C@@H](Nc1ccc2[nH]nc(\C=C\c3ccccn3)c2c1)c1cc(F)cc(F)c1

Trk-IN-20 is a 3-vinylindazole derivative compound that effectively inhibits the functions of Trk kinases. It accomplishes this by suppressing the phosphorylation of TrkA, TrkB, and TrkC, with IC50 values of 1.6 nM, 2.9 nM, and 2.0 nM, respectively [1].

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~