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HIT214434664
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HIT214434664
  • HIT ID:HIT214434664
  • Cas No:2529657-32-5
  • 常用名:Anticancer agent 63
  • IUPAC:2-[4-(2-methylpropyl)phenyl]-N-{3-[(trifluoromethyl)selanyl]propyl}propanamide
    IUPAC:2-[4-(2-methylpropyl)phenyl]-N-{3-[(trifluoromethyl)selanyl]propyl}propanamide
  • InChI key:YQWAFTSNGPUFSE-UHFFFAOYSA-N
  • 分子式:C17H24F3NOSe
  • 分子量:394.351
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CC(C)Cc1ccc(cc1)C(C)C(=O)NCCC[Se]C(F)(F)F
    SMILES:CC(C)Cc1ccc(cc1)C(C)C(=O)NCCC[Se]C(F)(F)F
  • Anticancer agent 63 (compound 3h) exhibits significant cytotoxic activity against multiple cancer cell lines, including SW480, HeLa, A549, and MCF-7, with IC 50 values of 4.9, 11.5, 9.4, and 3.4 μM, respectively, after 24 hours of treatment. In particular, Anticancer agent 63 induces apoptosis in MCF-7 cells by down-regulating Bcl-2 expression and up-regulating IL-2 and Caspase-3 expression. Additionally, Anticancer agent 63 demonstrates antioxidative properties [1].
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

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