Name: Cap-dependent endonuclease-IN-26
Rating: 5 (10 reviews)

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HIT ID:HIT214434675
Cas No:1370238-26-8
常用名:Cap-dependent endonuclease-IN-26
常用名:Cap-dependent endonuclease-IN-26
IUPAC:1-(diphenylmethyl)-5-hydroxy-3-(propan-2-yl)-1H,2H,3H,4H,6H-pyrido[2,1-f][1,2,4]triazine-4,6-dione
IUPAC:1-(diphenylmethyl)-5-hydroxy-3-(propan-2-yl)-1H,2H,3H,4H,6H-pyrido[2,1-f][1,2,4]triazine-4,6-dione
InChI key:XBUAYFHRCVFRFT-UHFFFAOYSA-N

分子式:C23H23N3O3
分子量:389.455
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC(C)N1CN(C(c2ccccc2)c2ccccc2)n2ccc(=O)c(O)c2C1=O
SMILES:CC(C)N1CN(C(c2ccccc2)c2ccccc2)n2ccc(=O)c(O)c2C1=O

Cap-dependent endonuclease-IN-26, a potent inhibitor of cap-dependent endonuclease (CEN) with an IC50 of 286 nM, exhibits significant antiviral activity against a broad spectrum of influenza A and B strains [1].

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