Name: AKR1C3-IN-6
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214435003
Cas No:2137881-54-8
常用名:AKR1C3-IN-6
IUPAC:4-hydroxy-1-[(4-methoxyphenyl)methyl]-N-[3-(trifluoromethyl)phenyl]-1H-1,2,3-triazole-5-carboxamide
IUPAC:4-hydroxy-1-[(4-methoxyphenyl)methyl]-N-[3-(trifluoromethyl)phenyl]-1H-1,2,3-triazole-5-carboxamide
InChI key:IMCLZLUHJZCWCW-UHFFFAOYSA-N

分子式:C18H15F3N4O3
分子量:392.338
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:COc1ccc(Cn2nnc(O)c2C(=O)Nc2cccc(c2)C(F)(F)F)cc1
SMILES:COc1ccc(Cn2nnc(O)c2C(=O)Nc2cccc(c2)C(F)(F)F)cc1

AKR1C3-IN-6 (Compound 1) is a powerful and specific inhibitor of AKR1C3, with IC50 values of 0.31 μM and 73.23 μM against AKR1C3 and AKR1C2, respectively. It demonstrates significant antitumor activity [1].

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~