LSD1-IN-14 | CAS 2698340-11-1 | AnyMole

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HIT214435327

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HIT214435327

HIT ID:HIT214435327
Cas No:2698340-11-1
常用名:LSD1-IN-14
IUPAC:N1-[2-(dimethylamino)ethyl]-N4-[5-(4-fluorophenyl)pyrimidin-2-yl]-N1-methylbenzene-1,4-diamine
IUPAC:N1-[2-(dimethylamino)ethyl]-N4-[5-(4-fluorophenyl)pyrimidin-2-yl]-N1-methylbenzene-1,4-diamine
InChI key:LELDTUUFZHHXFB-UHFFFAOYSA-N

分子式:C21H24FN5
分子量:365.456
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CN(C)CCN(C)c1ccc(Nc2ncc(cn2)-c2ccc(F)cc2)cc1
SMILES:CN(C)CCN(C)c1ccc(Nc2ncc(cn2)-c2ccc(F)cc2)cc1

LSD1-IN-14, a powerful and specific inhibitor of LSD1 (with an IC50 value of 0.89 μM), effectively suppresses the growth of A549 and THP-1 cells and promotes the apoptosis of tumor cells [1].

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6-8周
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¥ 10,600.00
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