Name: mGlu4 receptor agonist 1
Rating: 5 (10 reviews)

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结构编辑

类似物检索

HIT ID:HIT214435434
Cas No:1678501-16-0
常用名:mGlu4 receptor agonist 1
IUPAC:N-{4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]-3-methylphenyl}pyridine-2-carboxamide
IUPAC:N-{4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]-3-methylphenyl}pyridine-2-carboxamide
InChI key:RNDMJFKGWGEUBH-UHFFFAOYSA-N

分子式:C21H15ClN4O2
分子量:390.83
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:Cc1cc(NC(=O)c2ccccn2)ccc1-c1noc(n1)-c1ccccc1Cl
SMILES:Cc1cc(NC(=O)c2ccccn2)ccc1-c1noc(n1)-c1ccccc1Cl

mGlu4 receptor agonist 1 (compound 62) is a highly effective positive allosteric modulator of mGlu4 receptors, displaying an EC 50 of 308 nM. Additionally, it exhibits noteworthy anxiolytic and antipsychotic properties [1].

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