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HIT214435766
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HIT214435766
  • HIT ID:HIT214435766
  • Cas No:2490291-68-2
  • 常用名:Tubulin polymerization-IN-26
  • IUPAC:(2E)-3-(2-ethoxyphenyl)-N-[2-(6-methyl-1H-1,3-benzodiazol-2-yl)phenyl]prop-2-enamide
    IUPAC:(2E)-3-(2-ethoxyphenyl)-N-[2-(6-methyl-1H-1,3-benzodiazol-2-yl)phenyl]prop-2-enamide
  • InChI key:HOOYTCBSCZSMJT-FYWRMAATSA-N
  • 分子式:C25H23N3O2
  • 分子量:397.478
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCOc1ccccc1\C=C\C(=O)Nc1ccccc1-c1nc2ccc(C)cc2[nH]1
    SMILES:CCOc1ccccc1\C=C\C(=O)Nc1ccccc1-c1nc2ccc(C)cc2[nH]1
  • Tubulin polymerization-IN-26 (compound 12h) is a chemical compound that inhibits the polymerization of microtubulin. It achieves this by binding to the colchicine binding site of microtubulin, with an IC50 value of 4.64 μM. Additionally, Tubulin polymerization-IN-26 has the ability to induce apoptosis and inhibit cell metastasis or migration. Due to these properties, it holds potential as a valuable compound for researching lung cancer [1].
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

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