MPT0G211 mesylate | CAS 2151854-33-8 | AnyMole

有库存

HIT214436062

sdf 文件

结构编辑

类似物检索

HIT214436062

HIT ID:HIT214436062
Cas No:2151854-33-8
常用名:MPT0G211 mesylate
IUPAC:N-hydroxy-4-{[(quinolin-8-yl)amino]methyl}benzamide; methanesulfonic acid
IUPAC:N-hydroxy-4-{[(quinolin-8-yl)amino]methyl}benzamide; methanesulfonic acid
InChI key:PRIVCNWCWYRYNJ-UHFFFAOYSA-N

分子式:C18H19N3O5S
分子量:389.43
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CS(O)(=O)=O.ONC(=O)c1ccc(CNc2cccc3cccnc23)cc1
SMILES:CS(O)(=O)=O.ONC(=O)c1ccc(CNc2cccc3cccnc23)cc1

MPT0G211 mesylate is a powerful and selective HDAC6 inhibitor (IC50 = 0.291 nM), with high oral bioavailability. It exhibits remarkable selectivity for HDAC6 over other HDAC isoforms (>1000-fold selectivity). Additionally, MPT0G211 mesylate can effectively cross the blood-brain barrier. In preclinical studies using an Alzheimer's disease model, MPT0G211 mesylate has shown promising results in reducing tau phosphorylation and cognitive deficits. Furthermore, this compound exhibits anti-metastatic and neuroprotective effects, making it a potential candidate for anticancer interventions. [1] [2] [3].

市场产品/服务共显示1个结果

供应商
TargetMolSC
规格
货期
1-2周
纯度
-
¥ 10,600.00
1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

TargetMol | Target Loading

正在加载 ~