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  3. HIT214436106
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HIT214436106
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HIT214436106
  • HIT ID:HIT214436106
  • Cas No:1237541-73-9
  • 常用名:NAB-14
  • IUPAC:4-[(1H-indol-7-yl)carbamoyl]phenyl N,N-diethylcarbamate
    IUPAC:4-[(1H-indol-7-yl)carbamoyl]phenyl N,N-diethylcarbamate
  • InChI key:WCGIKJOMEYPSIP-UHFFFAOYSA-N
  • 分子式:C20H21N3O3
  • 分子量:351.406
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCN(CC)C(=O)Oc1ccc(cc1)C(=O)Nc1cccc2cc[nH]c12
    SMILES:CCN(CC)C(=O)Oc1ccc(cc1)C(=O)Nc1cccc2cc[nH]c12
  • NAB-14 is a powerful and selective chemical compound that acts as a non-competitive antagonist for GluN2C and GluN2D receptors. With an IC50 value of 580 nM for GluN1/GluN2D, NAB-14 demonstrates high potency. This compound exhibits a remarkable selectivity of more than 800-fold towards recombinant GluN2C and GluN2D when compared to GluN2A and GluN2B. Furthermore, NAB-14 possesses the ability to penetrate the blood-brain-barrier effectively [1].
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

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