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  3. HIT214436243
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HIT214436243
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HIT214436243
  • HIT ID:HIT214436243
  • Cas No:2721484-76-8
  • 常用名:Anti-inflammatory agent 22
  • IUPAC:2-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-5-hydroxyphenyl benzoate
    IUPAC:2-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-5-hydroxyphenyl benzoate
  • InChI key:SOPVGBOKHBQLRO-UXBLZVDNSA-N
  • 分子式:C22H16O6
  • 分子量:376.364
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:Oc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(OC(=O)c2ccccc2)c1
    SMILES:Oc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(OC(=O)c2ccccc2)c1
  • Anti-inflammatory agent 22 (compound 14a) is a potent orally active compound with anti-inflammatory properties. It effectively inhibits the production of TNF-α induced by LPS, exhibiting an IC50 value of 14.6 μM. Additionally, Anti-inflammatory agent 22 has demonstrated its ability to prevent adipogenesis and effectively suppress limb lymphedema volume in mice. This compound holds promise for the treatment of inflammation-related conditions, particularly lymphedematous tissue disorders [1].
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  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 14,900.00
    1

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