Name: EV-A71-IN-1
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT214436280
Cas No:2413648-96-9
常用名:EV-A71-IN-1
IUPAC:N-{[1,1'-biphenyl]-4-yl}-4-{imidazo[1,2-a]pyrimidin-3-yl}-1,3-thiazol-2-amine
IUPAC:N-{[1,1'-biphenyl]-4-yl}-4-{imidazo[1,2-a]pyrimidin-3-yl}-1,3-thiazol-2-amine
InChI key:RLAGELDZWDHQJS-UHFFFAOYSA-N

分子式:C21H15N5S
分子量:369.45
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:N(c1nc(cs1)-c1cnc2ncccn12)c1ccc(cc1)-c1ccccc1
SMILES:N(c1nc(cs1)-c1cnc2ncccn12)c1ccc(cc1)-c1ccccc1

EV-A71-IN-1 is a potent inhibitor of the human enterovirus A71 (EV-A71) capsid protein, with an EC50 of 0.27 μM against EV-A71. Acting as a capsid binder, EV-A71-IN-1 disrupts the crucial interaction between the viral VP1 protein and the host receptor hSCARB2. It displays broad-spectrum antiviral activity against various human enteroviruses, while being non-toxic to human cells (CC50 > 56.2 μM) [1].

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~