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HIT214982136
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HIT214982136
  • HIT ID:HIT214982136
  • Cas No:1313730-20-9
  • 常用名:ADMA-d6
  • IUPAC:(2S)-2-amino-5-[N',N'-di(2H3)methylcarbamimidamido]pentanoic acid dihydrochloride
    IUPAC:(2S)-2-amino-5-[N',N'-di(2H3)methylcarbamimidamido]pentanoic acid dihydrochloride
  • InChI key:SYLNVYJOPZWPJI-WTPXGJEESA-N
  • 分子式:C8H20Cl2N4O2
  • 分子量:281.21
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:Cl.Cl.[2H]C([2H])([2H])N(C(=N)NCCC[C@H](N)C(O)=O)C([2H])([2H])[2H]
    SMILES:Cl.Cl.[2H]C([2H])([2H])N(C(=N)NCCC[C@H](N)C(O)=O)C([2H])([2H])[2H]
  • NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA levels are increased concomitant with an increase in blood pressure in Dahl salt-sensitive rats fed a high-salt diet. ADMA levels are increased in the plasma in a variety of endothelial dysfunction-related diseases, including hypertension, congestive heart failure, and end-stage renal disease.
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  • 供应商
    TargetMolSC
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    货期
    35日内发货
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    ¥ 2,970.00
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