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  3. HIT214984065
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HIT214984065
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HIT214984065
  • HIT ID:HIT214984065
  • Cas No:591-28-6
  • 常用名:4-Thiouracil
  • 别名:NSC 43288, 4-TU, 4-Thiopyrimidin-2-one, 2-hydroxy-4-Mercaptopyrimidine
    别名:NSC 43288, 4-TU, 4-Thiopyrimidin-2-one, 2-hydroxy-4-Mercaptopyrimidine
  • IUPAC:4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one
    IUPAC:4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one
  • InChI key:OVONXEQGWXGFJD-UHFFFAOYSA-N
  • 分子式:C4H4N2OS
  • 分子量:128.15
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:O=c1[nH]ccc(=S)[nH]1
    SMILES:O=c1[nH]ccc(=S)[nH]1
  • 4-Thiouracil is a photoactivatable probe designated for site-specific applications in detecting RNA structures and nucleic acid-nucleic acid contacts. Upon illumination with ultraviolet light exceeding 300 nm and in the presence of oxygen, it serves as an energy donor, facilitating the generation of singlet oxygen through triplet-triplet energy transfer. This process enables the highly reactive oxygen species to interact with 4-thiouracil, leading to the formation of uracil and uracil-6-sulfonate; the latter exhibits fluorescence around a wavelength of approximately 390 nm. Additionally, 4-Thiouracil functions as a substrate for T. gondii uracil phosphoribosyltransferase, allowing the synthesis of 4-thiouridine monophosphate for subsequent integration into RNA.
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    TargetMolSC
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    ¥ 882.00
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  • 供应商
    BIONET-Key OrganicsBB
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    4-6周
    纯度
    -
    ¥ 2,922.00
    1

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