Name: Atiprimod (free base)
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT217588406
Cas No:123018-47-3
常用名:Atiprimod (free base)
IUPAC:(3-{8,8-dipropyl-2-azaspiro[4.5]decan-2-yl}propyl)diethylamine
IUPAC:(3-{8,8-dipropyl-2-azaspiro[4.5]decan-2-yl}propyl)diethylamine
InChI key:SERHTTSLBVGRBY-UHFFFAOYSA-N

分子式:C22H44N2
分子量:336.608
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CCCC1(CCC)CCC2(CCN(CCCN(CC)CC)C2)CC1
SMILES:CCCC1(CCC)CCC2(CCN(CCCN(CC)CC)C2)CC1

Atiprimod is an orally bioavailable small molecule belonging to the azaspirane class of cationic amphiphilic agents with anti-inflammatory, antineoplastic, and antiangiogenic properties. Atiprimod inhibits the phosphorylation of signal transducer and activator of transcription 3 (STAT3), blocking the signalling pathways of interleukin-6 and vascular endothelial growth factor (VEGF) and downregulating the anti-apoptotic proteins Bcl-2, Bcl-XL, and Mcl-1, thereby inhibiting cell proliferation, inducing cell cycle arrest, and inducing apoptosis.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~