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  3. HIT217588435
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HIT217588435
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HIT217588435
  • HIT ID:HIT217588435
  • Cas No:1246815-11-1
  • 常用名:Racecadotril-d5
  • IUPAC:[(2,3,4,5,6-2H5)phenyl]methyl 2-{2-[(acetylsulfanyl)methyl]-3-phenylpropanamido}acetate
    IUPAC:[(2,3,4,5,6-2H5)phenyl]methyl 2-{2-[(acetylsulfanyl)methyl]-3-phenylpropanamido}acetate
  • InChI key:ODUOJXZPIYUATO-LKOJFEAXSA-N
  • 分子式:C21H23NO4S
  • 分子量:390.51
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:[2H]c1c([2H])c([2H])c(COC(=O)CNC(=O)C(CSC(C)=O)Cc2ccccc2)c([2H])c1[2H]
    SMILES:[2H]c1c([2H])c([2H])c(COC(=O)CNC(=O)C(CSC(C)=O)Cc2ccccc2)c([2H])c1[2H]
  • Racecadotril-d5 is intended for use as an internal standard for the quantification of racecadotril by GC- or LC-MS. Racecadotril is a prodrug form of the neprilysin (NEP) inhibitor thiorphan. In vivo, racecadotril reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats when administered at doses of 80 or 100 mg/kg, respectively. It also decreases the duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-induced diarrhea. Formulations containing racecadotril have been used in the treatment of acute diarrhea.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 1,230.00
    1

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