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  3. HIT217590848
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HIT217590848
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HIT217590848
  • HIT ID:HIT217590848
  • Cas No:88859-04-5
  • 常用名:Mafosfamide
  • IUPAC:2-{[(4R)-2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2lambda5-oxazaphosphinan-4-yl]sulfanyl}ethane-1-sulfonic acid
    IUPAC:2-{[(4R)-2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2lambda5-oxazaphosphinan-4-yl]sulfanyl}ethane-1-sulfonic acid
  • InChI key:PBUUPFTVAPUWDE-HSLMEMBISA-N
  • 分子式:C9H19Cl2N2O5PS2
  • 分子量:401.25
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:OS(=O)(=O)CCS[C@@H]1CCOP(=O)(N1)N(CCCl)CCCl
    SMILES:OS(=O)(=O)CCS[C@@H]1CCOP(=O)(N1)N(CCCl)CCCl
  • Mafosfamide is a synthetic oxazaphosphorine derivative with antineoplastic properties. Mafosfamide alkylates DNA, forming DNA cross-links and inhibiting DNA synthesis. Although closely related to cyclophosphamide, mafosfamide, unlike cyclophosphamide, does not require hepatic activation to generate its active metabolite 4-hydroxy-cyclophosphamide; accordingly, mafosfamide is potentially useful in the intrathecal treatment of neoplastic meningitis.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

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