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- HIT ID:HIT217597569
- Cas No:180001-34-7
- 常用名:1400W
- 别名:W1400
- InChI key:RODUKNYOEVZQPR-UHFFFAOYSA-N
- 分子式:C10H15N3
- 分子量:177.251
- 氢键供体数 (HBD):
- 氢键受体数 (HBA):
- LogP:
- 1400W is a slow, tight-binding, and highly selective inducible nitric-oxide synthase (iNOS) inhibitor, with a K_d value ≤ 7 nM. 1400W inhibits iNOS induction in microglial cells and reduces the generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation [1] [2].
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- 供应商TargetMol规格货期10-14周纯度-待询1
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