Name: Palmitoleic Acid sodium
Rating: 5 (10 reviews)

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HIT ID:HIT217607652
Cas No:
常用名:Palmitoleic Acid sodium
别名:cis-Palmitoleic Acid, C16:1(9Z), C16:1 n-7, (9Z)-Hexadecenoic Acid
别名:cis-Palmitoleic Acid, C16:1(9Z), C16:1 n-7, (9Z)-Hexadecenoic Acid
IUPAC:sodium (9Z)-hexadec-9-enoate
IUPAC:sodium (9Z)-hexadec-9-enoate
InChI key:AQADNICIQOBXGR-CFYXSCKTSA-M

分子式:C16H29NaO2
分子量:276.396
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[Na+].CCCCCC\C=C/CCCCCCCC([O-])=O
SMILES:[Na+].CCCCCC\C=C/CCCCCCCC([O-])=O

Palmitoleic acid, an ω-7 monounsaturated fatty acid found in macadamia and sea buckthorn oils, enhances both basal and insulin-stimulated glucose uptake, as well as Glut4 protein levels in 3T3-L1 adipocytes at a 200 µM concentration. Ex vivo, at a dosage of 300 mg/kg per day, it significantly increases glucose uptake and both aerobic and anaerobic glycolysis, while decreasing de novo fatty acid synthesis and the activity of lipogenic enzymes, specifically ATP citrate lyase (ACL) and glucose-6-phosphate dehydrogenase (G6PDH), in isolated murine adipocytes. Furthermore, the dietary administration of palmitoleic acid at 300 mg/kg mitigates high-fat diet-induced insulin resistance and liver inflammation in mice.

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