Name: D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
Rating: 5 (10 reviews)

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HIT ID:HIT217612752
Cas No:
常用名:D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
常用名:D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
IUPAC:octasodium (1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonatooxy)cyclohexyl phosphate
IUPAC:octasodium (1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonatooxy)cyclohexyl phosphate
InChI key:QYQMPPDYTHNACQ-ZOJXHACUSA-F

分子式:C6H8Na8O18P4
分子量:675.925
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](OP([O-])([O-])=O)[C@H](O)[C@@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H]1OP([O-])([O-])=O
SMILES:[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](OP([O-])([O-])=O)[C@H](O)[C@@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H]1OP([O-])([O-])=O

D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)-P4 increases intracellular calcium levels by two distinct mechanisms: opening calcium channels on both the endoplasmic reticulum to release calcium from internal stores and on the plasma membrane to allow the influx of calcium from outside the cell.

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