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  3. HIT217643415
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HIT217643415
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HIT217643415
  • HIT ID:HIT217643415
  • Cas No:196391-82-9
  • 常用名:Prosaptide TX14(A)
  • IUPAC:(4S)-4-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2R)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]propanamido]-4-methylpentanamido]-3-methylpentanamido]-3-carboxypropanamido]-3-carbamoylpropanamido]-3-carbamoylpropanamido]propanamido]-3-hydroxybutanamido]-4-{[(1S)-3-carboxy-1-{[(1S,2S)-1-{[(1S)-1-{[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-methylbutyl]carbamoyl}propyl]carbamoyl}butanoic acid
    IUPAC:(4S)-4-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2R)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]propanamido]-4-methylpentanamido]-3-methylpentanamido]-3-carboxypropanamido]-3-carbamoylpropanamido]-3-carbamoylpropanamido]propanamido]-3-hydroxybutanamido]-4-{[(1S)-3-carboxy-1-{[(1S,2S)-1-{[(1S)-1-{[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-methylbutyl]carbamoyl}propyl]carbamoyl}butanoic acid
  • InChI key:SMUKRAODILXPSW-SRWCCNGVSA-N
  • 分子式:C69H110N16O26
  • 分子量:1579.725
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)[C@@H](N)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
    SMILES:CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)[C@@H](N)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
  • Potent GPR37L1 and GPR37 agonist (EC50 values are 5 and 7 nM, respectively). Stimulates signaling through pertussis toxin-sensitive G proteins. Stimulates ERK phosphorylation. Protects against cellular stress. Promotes myelin lipid synthesis and prolongs cell survival in both Schwann cells and oligodendrocytes; neuroprotective and glioprotective.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 5,750.00
    1

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