Name: Varespladib sodium
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT217654197
Cas No:
常用名:Varespladib sodium
别名:伐瑞拉地钠, 伐瑞拉迪钠, LY315920 sodium
IUPAC:sodium 2-{[1-benzyl-3-(carbamoylcarbonyl)-2-ethyl-1H-indol-4-yl]oxy}acetate
IUPAC:sodium 2-{[1-benzyl-3-(carbamoylcarbonyl)-2-ethyl-1H-indol-4-yl]oxy}acetate
InChI key:XZZUHXILQXLTGV-UHFFFAOYSA-M

分子式:C21H19N2NaO5
分子量:402.382
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[Na+].CCc1c(C(=O)C(N)=O)c2c(OCC([O-])=O)cccc2n1Cc1ccccc1
SMILES:[Na+].CCc1c(C(=O)C(N)=O)c2c(OCC([O-])=O)cccc2n1Cc1ccccc1

Varespladib sodium (LY315920 sodium) is a highly potent and selective inhibitor of group IIA secretory phospholipase A2 (sPLA2), with an IC50 of 9 nM. It demonstrates significant inhibitory activity against sPLA2 in serum samples from multiple species, including rat, rabbit, guinea pig, and human, with IC50 values of 8.1 nM, 5.0 nM, 3.2 nM, and 6.2 nM, respectively.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~