Name: 10-SAHSA
Rating: 5 (10 reviews)

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HIT ID:HIT217656439
Cas No:
常用名:10-SAHSA
IUPAC:10-(octadecanoyloxy)octadecanoic acid
IUPAC:10-(octadecanoyloxy)octadecanoic acid
InChI key:KARVIOOFYPUCOA-UHFFFAOYSA-N

分子式:C36H70O4
分子量:566.952
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CCCCCCCCCCCCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCCC(O)=O
SMILES:CCCCCCCCCCCCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCCC(O)=O

10-SAHSA, an endogenous lipid recently discovered, is part of the FAHFAs, a group of branched fatty acid esters of hydroxy fatty acids. It specifically consists of stearic acid esterified to 10-hydroxy stearic acid. Notably, PAHSAs, closely related to 10-SAHSA, are significantly present in the adipose tissue of AG4OX mice that are glucose tolerant due to the overexpression of the Glut4 glucose transporter in their adipose tissue. Similar to other FAHFAs, which are known to improve glucose tolerance, promote insulin secretion, and possess anti-inflammatory properties, 10-SAHSA is considered a potential bioactive lipid with implications for metabolic syndrome and inflammation management.

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