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HIT217694620
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HIT217694620
  • HIT ID:HIT217694620
  • Cas No:85405-05-6
  • 常用名:2-O-methyl PAF C-16
  • IUPAC:3-(hexadecyloxy)-2-methoxypropyl 2-(trimethylazaniumyl)ethyl phosphate
    IUPAC:3-(hexadecyloxy)-2-methoxypropyl 2-(trimethylazaniumyl)ethyl phosphate
  • InChI key:RZNRKXGAJMGLIM-UHFFFAOYSA-N
  • 分子式:C25H54NO6P
  • 分子量:495.682
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCCCCCCCCCCCCCCCOCC(COP([O-])(=O)OCC[N+](C)(C)C)OC
    SMILES:CCCCCCCCCCCCCCCCOCC(COP([O-])(=O)OCC[N+](C)(C)C)OC
  • 2-O-methyl PAF C-16 is a synthetic analog of platelet-activating factor (PAF) featuring a methyl group attached via an ether linkage at the sn-2 position. While the specific biological activities of 2-O-methyl PAF C-16 remain undercharacterized, studies with its C-18 counterpart have demonstrated its ability to modulate various biological processes. These processes include reducing plasma membrane fluidity and hindering the invasiveness of tumor cells in embryonic chick hearts. Furthermore, in rat astrocytes, the C-18 analog prompts the release of significant amounts of nitric oxide (NO) through a mechanism that involves the activation of nitric oxide synthase (NOS).
市场产品/服务共显示2个结果
  • 供应商
    TargetMolSC
    规格
    货期
    8-10周
    纯度
    -
    待询
    1
  • 供应商
    TargetMolSC
    规格
    货期
    待询
    纯度
    -
    待询
    1

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