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  3. HIT218432815
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HIT218432815
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HIT218432815
  • HIT ID:HIT218432815
  • Cas No:
  • 常用名:2-Linoleoyl Glycerol
  • 别名:2-LG
  • IUPAC:1,3-dihydroxypropan-2-yl octadeca-9,12-dienoate
    IUPAC:1,3-dihydroxypropan-2-yl octadeca-9,12-dienoate
  • InChI key:IEPGNWMPIFDNSD-UHFFFAOYSA-N
  • 分子式:C21H38O4
  • 分子量:354.531
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCCCCC=CCC=CCCCCCCCC(=O)OC(CO)CO
    SMILES:CCCCCC=CCC=CCCCCCCCC(=O)OC(CO)CO
  • 2-Arachidonoyl glycerol (2-AG), a natural endocannabinoid ligand for the CB1 receptor, was isolated from porcine brain and characterized. Its congener, 2-linoleoyl glycerol (2-LG), which has a linoleoyl group instead of an arachidonoyl group, also exists alongside 2-AG in vivo. While 2-LG exhibits low intrinsic activity, it enhances the activity of 2-AG and other endocannabinoids through an "entourage" effect, attributed to the inhibition of breakdown and reuptake pathways that typically decrease endocannabinoid levels post-release.
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  • 供应商
    TargetMolSC
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    货期
    35日内发货
    纯度
    -
    ¥ 465.00
    1

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