Name: Heneicosapentaenoic Acid ethyl ester
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HIT ID:HIT218615171
Cas No:
Common Name:Heneicosapentaenoic Acid ethyl ester
Common Name:Heneicosapentaenoic Acid ethyl ester
alias:HPA ethyl ester
IUPAC:ethyl henicosa-6,9,12,15,18-pentaenoate
IUPAC:ethyl henicosa-6,9,12,15,18-pentaenoate
InChIKey:RKAKAVQIMCZXPE-UHFFFAOYSA-N

Molecular Formula:C23H36O2
Molecular Weight:344.539
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CCOC(=O)CCCCC=CCC=CCC=CCC=CCC=CCC
SMILES:CCOC(=O)CCCCC=CCC=CCC=CCC=CCC=CCC

Heneicosapentaenoic Acid (HPA), a 21:5 ω-3 fatty acid, is found in minute quantities in green algae and fish oils, resembling eicosapentaenoic acid (EPA) but with an added carbon on the carboxyl end, positioning the initial double bond at the Δ6 location. HPA serves as a tool for examining the impact of double bond positions within n-3 fatty acids, as it is incorporated into phospholipids and triacylglycerol in vivo as efficiently as EPA and docosahexaenoic acid (DHA), while significantly inhibiting the synthesis of arachidonic acid from linoleic acid. Moreover, the ethyl ester variant of heneicosapentaenoic acid offers a more lipophilic and stable alternative to the free acid form.

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