Name: Anti-melanoma agent 3
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HIT ID:HIT218615183
Cas No:1253697-49-2
Common Name:Anti-melanoma agent 3
IUPAC:5-(4-fluorobenzoyl)-2-(4-methoxyphenyl)-1H-imidazole
IUPAC:5-(4-fluorobenzoyl)-2-(4-methoxyphenyl)-1H-imidazole
InChI key:VKXVLHQVMBNLHX-UHFFFAOYSA-N

Molecular Formula:C17H13FN2O2
Molecular Weight:296.301
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:COc1ccc(cc1)-c1ncc([nH]1)C(=O)c1ccc(F)cc1
SMILES:COc1ccc(cc1)-c1ncc([nH]1)C(=O)c1ccc(F)cc1

Compound 5cb, known as Anti-melanoma agent 3, is a derivative of 2-aryl-4-benzoyl-imidazole (ABI) that acts as an inhibitor of melanoma xenogeneic tumors. It exhibits anticancer effects by targeting the colchicine binding site, thereby preventing tubulin polymerization [1].

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