Name: Dihomo-γ-Linolenic Acid ethyl ester
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HIT ID:HIT218615277
Cas No:
Common Name:Dihomo-γ-Linolenic Acid ethyl ester
Common Name:Dihomo-γ-Linolenic Acid ethyl ester
alias:ethyl 20:3ω6
IUPAC:ethyl icosa-8,11,14-trienoate
IUPAC:ethyl icosa-8,11,14-trienoate
InChIKey:XJXHWCQMUAZGAN-UHFFFAOYSA-N

Molecular Formula:C22H38O2
Molecular Weight:334.544
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CCCCCC=CCC=CCC=CCCCCCCC(=O)OCC
SMILES:CCCCCC=CCC=CCC=CCCCCCCC(=O)OCC

Ethyl dihomo-γ-linolenic acid ethyl ester (ethyl DGLA), an ω-6 fatty acid intermediate ester form, elevates prostaglandin E1(PGE1) and PGE2 secretion in rabbit renal papilla when administered dietarily at a dosage of 1 g/kg per day for 25 days. Additionally, this dosage of ethyl DGLA increases triglyceride levels and enhances the proportion of 20:3ω6 and 20:4ω6 phospholipids in the renal medulla of rabbits. Ethyl DGLA formulations have been employed in managing eczema and inflammatory disorders.

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