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  3. HIT218615402
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HIT218615402
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HIT218615402
  • HIT ID:HIT218615402
  • Cas No:
  • 常用名:9-POHSA
  • IUPAC:9-(hexadec-9-enoyloxy)octadecanoic acid
    IUPAC:9-(hexadec-9-enoyloxy)octadecanoic acid
  • InChI key:VCXRHEIVUHPWLL-UHFFFAOYSA-N
  • 分子式:C34H64O4
  • 分子量:536.882
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCCCCCCCCC(CCCCCCCC(O)=O)OC(=O)CCCCCCCC=CCCCCCC
    SMILES:CCCCCCCCCC(CCCCCCCC(O)=O)OC(=O)CCCCCCCC=CCCCCCC
  • Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are recent discoveries in endogenous lipids that are influenced by dietary changes such as fasting and high-fat diets, showing a link with enhanced insulin sensitivity in mice. These compounds typically feature a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) bound to a hydroxy group on another C-16 or C-18 fatty chain. A specific FAHFA, 9-POHSA, consists of palmitoleic acid connected at the hydroxy stearic acid’s 9th position. This molecule, in particular, exhibits notably increased levels in the serum of glucose-tolerant AG4OX mice, which express the Glut4 glucose transporter predominantly in their adipose tissue. Given the broader family of FAHFAs' roles in enhancing glucose tolerance, promoting insulin secretion, and exerting anti-inflammatory effects, 9-POHSA emerges as a potential bioactive lipid involved in managing metabolic syndrome and inflammation.
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  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 1,290.00
    1

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