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  3. HIT218638201
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HIT218638201
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HIT218638201
  • HIT ID:HIT218638201
  • Cas No:
  • 常用名:Δ12-Prostaglandin D2
  • 别名:Δ12-PGD2
  • IUPAC:7-[5-hydroxy-2-(3-hydroxyoctylidene)-3-oxocyclopentyl]hept-5-enoic acid
    IUPAC:7-[5-hydroxy-2-(3-hydroxyoctylidene)-3-oxocyclopentyl]hept-5-enoic acid
  • InChI key:OBTVQKDILGZFPY-UHFFFAOYSA-N
  • 分子式:C20H32O5
  • 分子量:352.471
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCCCCC(O)CC=C1C(CC=CCCCC(O)=O)C(O)CC1=O
    SMILES:CCCCCC(O)CC=C1C(CC=CCCCC(O)=O)C(O)CC1=O
  • Prostaglandin D2 (PGD2) is a primary enzymatic prostaglandin derived from PGH2 and is abundantly produced in the cerebrospinal fluid (CSF) by the lipocalin-type PGD synthase, and peripherally by myeloid cells such as mast cells and basophils via a hematopoietic-type PGD synthase. PGD2 is chemically unstable and presents challenges for use and analysis due to its brief in vivo half-life. Δ12-PGD2, an initial decomposition product of PGD2, acts as an intermediate in the pathway to Δ12-PGJ2, a cyclopentenone prostaglandin known for its antimitotic and carcinogenic properties. The metabolism of Δ12-PGD2 involves the addition of thiol nucleophiles, a common pathway for many cyclopentenone prostaglandins.
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  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 1,530.00
    1

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