Name: AMC Arachidonoyl Amide
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HIT ID:HIT218638358
Cas No:
Common Name:AMC Arachidonoyl Amide
alias:AMC-AA
IUPAC:N-(4-methyl-2-oxo-2H-chromen-7-yl)icosa-5,8,11,14-tetraenamide
IUPAC:N-(4-methyl-2-oxo-2H-chromen-7-yl)icosa-5,8,11,14-tetraenamide
InChIKey:IQPBUDMTXHWSHB-UHFFFAOYSA-N

Molecular Formula:C30H39NO3
Molecular Weight:461.646
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CCCCCC=CCC=CCC=CCC=CCCCC(=O)Nc1ccc2c(C)cc(=O)oc2c1
SMILES:CCCCCC=CCC=CCC=CCC=CCCCC(=O)Nc1ccc2c(C)cc(=O)oc2c1

Arachidonoyl amide (AMC-AA) is a fatty acid amide among several that serve to quantify fatty acid amide hydrolase (FAAH) activity. FAAH, with its relative lack of selectivity, processes various amide head groups beyond ethanolamine, the head group of its primary endogenous substrate, anandamide (AEA). The interaction of AMC-AA with FAAH leads to the liberation of fluorescent aminomethyl coumarin, which has an absorption peak at 360 nm and emission at 465 nm. This fluorescence release facilitates the rapid and efficient assessment of FAAH activity through the utilization of either a standard cuvette or a microplate fluorometer.

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