Name: (±)-PPCC oxalate
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HIT ID:HIT218639116
Cas No:1781628-91-8
Common Name:(±)-PPCC oxalate
IUPAC:methyl (1S,2R)-2-[(4-hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropane-1-carboxylate; oxalic acid
IUPAC:methyl (1S,2R)-2-[(4-hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropane-1-carboxylate; oxalic acid
InChI key:PEFYUSZBWILOFC-NXCGSPNESA-N

Molecular Formula:C26H31NO7
Molecular Weight:469.534
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:OC(=O)C(O)=O.COC(=O)[C@]1(C[C@H]1CN1CCC(O)(CC1)c1ccccc1)c1ccc(C)cc1
SMILES:OC(=O)C(O)=O.COC(=O)[C@]1(C[C@H]1CN1CCC(O)(CC1)c1ccccc1)c1ccc(C)cc1

(±)-PPCC oxalate, a sigma-1 agonist with a K i of 1.5 nM, primarily targets sigma-1 receptors and exhibits significant anti-amnesia effects in rats with mild or severe cognitive impairment, enhancing their cognitive abilities [1].

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