Name: Sandoz 58-035
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HIT ID:HIT218639738
Cas No:78934-83-5
Common Name:Sandoz 58-035
alias:Sandoz58-035
IUPAC:3-(decyldimethylsilyl)-N-[2-(4-methylphenyl)-1-phenylethyl]propanamide
IUPAC:3-(decyldimethylsilyl)-N-[2-(4-methylphenyl)-1-phenylethyl]propanamide
InChI key:NBYATBIMYLFITE-UHFFFAOYSA-N

Molecular Formula:C30H47NOSi
Molecular Weight:465.797
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CCCCCCCCCC[Si](C)(C)CCC(=O)NC(Cc1ccc(C)cc1)c1ccccc1
SMILES:CCCCCCCCCC[Si](C)(C)CCC(=O)NC(Cc1ccc(C)cc1)c1ccccc1

Sandoz 58-035 acts as a competitive inhibitor of cholesterol acyltransferase (ACAT), significantly blocking (>98%) the hormonally stimulated esterification of cholesterol within cells. Sandoz 58-035 is therefore used in lipid metabolism and enzymology research systems to investigate ACAT-dependent cholesterol esterification processes, intracellular cholesterol trafficking, and regulation of sterol storage pathways in cellular models of lipid homeostasis.

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