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HIT218645516
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HIT218645516
  • HIT ID:HIT218645516
  • Cas No:
  • Common Name:Isoreserpiline
  • alias:3-Isoreserpilinic Acid, methyl ester
  • IUPAC:methyl 6,7-dimethoxy-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8,18-pentaene-19-carboxylate
    IUPAC:methyl 6,7-dimethoxy-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8,18-pentaene-19-carboxylate
  • InChIKey:FGWJRZQNNZVCHR-UHFFFAOYSA-N
  • Molecular Formula:C23H28N2O5
  • Molecular Weight:412.486
  • Hydrogen Bond Donor (HBD):
  • Hydrogen Bond Acceptor (HBA):
  • LogP:
  • SMILES:COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5cc(OC)c(OC)cc45)C3CC12
    SMILES:COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5cc(OC)c(OC)cc45)C3CC12
  • Isoreserpiline, an indole alkaloid discovered in R. tetraphylla, exhibits a range of biological activities. This compound enhances the antibacterial efficacy of nalidixic acid against both nalidixic acid-sensitive and -resistant E. coli strains through a synergistic effect. Additionally, at a dosage of 25 mg/kg, it mitigates amphetamine-induced hyperactivity in mice.
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  • Supplier
    TargetMolSC
    Pack Size
    Estimated Lead Time
    35 days
    Purity
    -
    $ 617.00
    1

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