Name: TEAD-IN-6
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HIT ID:HIT218648140
Cas No:2821763-12-4
Common Name:TEAD-IN-6
IUPAC:N-methyl-5-{5H,6H,7H-pyrrolo[1,2-a]imidazol-2-yl}-6-[4-(trifluoromethyl)phenoxy]pyridine-3-sulfonamide
IUPAC:N-methyl-5-{5H,6H,7H-pyrrolo[1,2-a]imidazol-2-yl}-6-[4-(trifluoromethyl)phenoxy]pyridine-3-sulfonamide
InChI key:UNZNMUZYUKSBBZ-UHFFFAOYSA-N

Molecular Formula:C19H17F3N4O3S
Molecular Weight:438.43
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CNS(=O)(=O)c1cnc(Oc2ccc(cc2)C(F)(F)F)c(c1)-c1cn2CCCc2n1
SMILES:CNS(=O)(=O)c1cnc(Oc2ccc(cc2)C(F)(F)F)c(c1)-c1cn2CCCc2n1

TEAD-IN-6 (Example 11-1) is a TEAD modulator that inhibits the YAP1/TAZ-TEAD interaction and has applications in cancer research [1].

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