Name: UE2343
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HIT ID:HIT218658945
Cas No:1346013-80-6
Common Name:UE2343
alias:UE-2343, UE 2343
IUPAC:(1R,3R,5S)-8-[5-(1H-pyrazol-4-yl)thiophene-3-carbonyl]-3-(pyrimidin-2-yl)-8-azabicyclo[3.2.1]octan-3-ol
IUPAC:(1R,3R,5S)-8-[5-(1H-pyrazol-4-yl)thiophene-3-carbonyl]-3-(pyrimidin-2-yl)-8-azabicyclo[3.2.1]octan-3-ol
InChI key:MMZFGTAMARVHAF-QWHZDKJVSA-N

Molecular Formula:C19H19N5O2S
Molecular Weight:381.45
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:O[C@@]1(C[C@@H]2CC[C@H](C1)N2C(=O)c1csc(c1)-c1cn[nH]c1)c1ncccn1
SMILES:O[C@@]1(C[C@@H]2CC[C@H](C1)N2C(=O)c1csc(c1)-c1cn[nH]c1)c1ncccn1

UE2343 is a brain-penetrant, orally active 11β-HSD1 inhibitor for Alzheimer's disease research.

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